- Year of foundation: 1944
- Location: San Mateo, California, USA
- Grades Offered: 9-12
- School Type: Boys
- Students Enrolled: 830
Junípero Serra High School is a Catholic college preparatory high school in San Mateo, California, United States, serving students in grades 9–12. A part of the Roman Catholic Archdiocese of San Francisco, this school provides education for young men. It is a community of parents, teachers, staff members, and alumni dedicated to providing the best high school experience possible for the young men of the San Francisco Bay Area. Each student is valued and knows that he belongs. Serra offers a rigorous college preparatory curriculum, which includes a rich diversity of classes and an extensive array of AP and Honors courses. The students become compassionate leaders who care about their communities and are passionate about making a difference in the world. The lifelong friendships are examples of the strength of the brotherhood and are alive in our inclusive community.